Description

4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Yl] is a high-value, multi-functional naphthalene-based boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to build novel molecular architectures for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific naphthalene-based structures.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for creating advanced organic semiconductors and charge-transport materials used in display and lighting technologies.
• Polymer & Material Science: Enables the synthesis of functionalized polymers, liquid crystals, and other specialty materials with tailored electronic or optical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands used in homogeneous catalysis.

Basic Information

Item	Details
Product Name	4,4,5,5-Tetramethyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Yl]
CAS No.	929103-36-6
Molecular Formula	C24H33BO4
Molecular Weight	396.33 g/mol
Synonyms	1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 1,4-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 1,4-Naphthalenediboronic acid bis(pinacol) ester; 1,4-Bis(pinacolboranyl)naphthalene; 1,4-Naphthalene bis(boronic acid pinacol ester); 1,4-Naphthalene diboronic acid pinacol ester; 1,4-Naphthalenediyldiboronic acid bis(pinacol ester); Naphthalene-1,4-diylbis(boronic acid pinacol ester)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR (1H and 13C), and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support development and production needs across various grades, from research to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.