Description

3-Nitro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine is a high-value, multi-functional aromatic amine boronic ester derivative, serving as a critical synthetic intermediate. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl or complex aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic amine functionalities.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, conductive polymers, and liquid crystals.
• Cross-Coupling Reactions (Suzuki-Miyaura): The pinacol boronate ester group makes it an ideal partner for palladium-catalyzed cross-coupling with aryl halides, enabling efficient carbon-carbon bond formation.
• Chemical Research & Library Synthesis: Employed in medicinal and combinatorial chemistry for the rapid generation of diverse compound libraries for screening.
• Ligand & Catalyst Preparation: Useful in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Nitro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine
CAS No.	928847-00-1
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	2-(4-Amino-2-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Amino-3-nitrophenylboronic acid pinacol ester; 3-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-nitroaniline; 928847-00-1; ANBP; 4-Amino-3-nitrophenyl-Bpin
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for all shipments. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.