Description

Chromone-6-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex chromone-based molecular frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create novel chromone derivatives for biological screening.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential therapeutic agents, including kinase inhibitors and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of new active ingredients with herbicidal or fungicidal properties.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and light-emitting materials due to the chromone scaffold's electronic properties.
• Chemical Biology & Probe Development: Facilitates the creation of molecular probes for studying enzyme function and biological pathways.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	Chromone-6-Boronic Acid Pinacol Ester
CAS No.	928773-42-6
Molecular Formula	C₁₅H₁₇BO₄
Molecular Weight	272.11 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chromone; 2H-1-Benzopyran-2-one, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Chromone-6-boronic acid pinacol ester; 6-(Pinacolatoboryl)chromone; 6-Chromoneboronic Acid Pinacol Ester; 6-Boronochromone Pinacol Ester
EINECS	Contact for details

Quality Control

Every batch of Chromone-6-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, HPLC, and GC-MS to ensure identity, purity, and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.