Description

1,3-Cyclohexadiene-1-Carbonitrile, 6-Amino-4-Chloro- is a high-purity, functionalized cyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex heterocyclic systems and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific amino-chloro-substituted diene motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging its reactive diene and nitrile functionalities.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects requiring precise, multi-functional cyclic structures.
• Academic and R&D Laboratories: Utilized in methodological studies and the exploration of new cycloaddition and functionalization reactions.

Basic Information

Product Name	1,3-Cyclohexadiene-1-Carbonitrile, 6-Amino-4-Chloro-
CAS No.	928715-99-5
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	6-Amino-4-chloro-1,3-cyclohexadiene-1-carbonitrile; 4-Chloro-6-amino-1,3-cyclohexadiene-1-carbonitrile; 1-Cyano-6-amino-4-chloro-1,3-cyclohexadiene; 4-Chloro-6-aminocyclohexa-1,3-diene-1-carbonitrile; 6-Amino-4-chlorocyclohexa-1,3-diene-1-carbonitrile; (6-Amino-4-chlorocyclohexa-1,3-dien-1-yl)methanenitrile
EINECS	Contact for details

Quality Control

Our 1,3-Cyclohexadiene-1-Carbonitrile, 6-Amino-4-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.