Description

4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanesulfonamide is a high-value organoboron building block designed for advanced synthetic chemistry. This compound is critical for enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and agrochemical research. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing sulfonamide or arylboronic ester motifs.
• Suzuki-Miyaura Cross-Coupling: Enables the formation of carbon-carbon bonds between its boronic ester group and various aryl/vinyl halides, a cornerstone reaction in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-sulfonamide structures.
• Materials Science Research: Serves as a precursor for creating functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity boronic ester derivatives.

Basic Information

Item	Detail
Product Name	4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanesulfonamide
CAS No.	928657-23-2
Molecular Formula	C13H20BNO4S
Molecular Weight	297.18 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanesulfonamide; 4-(Pinacolatoboryl)benzenemethanesulfonamide; 4-(Pinacolboron)benzenemethanesulfonamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylmethanesulfonamide; Benzenemethanesulfonamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; (4-(Aminosulfonylmethyl)phenyl)boronic acid pinacol ester; 4-(Pinacolatoboryl)phenylmethanesulfonamide
EINECS	Contact for details

Quality Control

Our production of 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzenemethanesulfonamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.