Description

5-Acetamido-2-Aminophenylboronic Acid is a bifunctional aromatic boronic acid derivative that serves as a versatile intermediate in advanced organic synthesis. Its molecular structure, featuring both a boronic acid group and protected amine functionality, makes it a critical building block for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Essential boronic acid component for forming carbon-carbon bonds in medicinal chemistry and materials science.
• Protease Inhibitor Development: Used in research for creating inhibitors that target specific enzymatic pathways.
• Bioconjugation and Probe Synthesis: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Ligand for Sensor Development: Employed in the design of chemical sensors and assays due to its selective binding properties.
• Advanced Material Synthesis: Building block for organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Acetamido-2-Aminophenylboronic Acid
CAS No.	136237-73-5
Molecular Formula	C8H11BN2O3
Molecular Weight	194.00 g/mol
Synonyms	5-Acetamido-2-aminobenzeneboronic acid; 2-Amino-5-acetamidophenylboronic acid; (5-Acetamido-2-aminophenyl)boronic acid; B-(5-Acetamido-2-aminophenyl)boronic acid; 5-Acetamidoanthranilic acid boronic acid; N-[5-(Boronyl)-2-aminophenyl]acetamide; 136237-73-5; 5-Acetamido-2-aminophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Acetamido-2-Aminophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.