Description

2-(4-Boc-Aminophenyl)Benzoic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecules where precise control over amino group reactivity is essential. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptides, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate protected phenylalanine-like structures.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications.

Basic Information

Product Name	2-(4-Boc-Aminophenyl)Benzoic Acid
CAS No.	927801-54-5
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	2-[(4-{[(Tert-Butoxy)Carbonyl]Amino}Phenyl)]Benzoic Acid; 2-(4-((Tert-Butoxycarbonyl)Amino)Phenyl)Benzoic Acid; 4'-(Boc-Amino)-[1,1'-Biphenyl]-2-Carboxylic Acid; 2-(4-(Boc-Amino)Phenyl)Benzoic Acid; 2-(4-(Tert-Butoxycarbonylamino)Phenyl)Benzoic Acid; Biphenyl-2-Carboxylic Acid, 4'-(Boc-Amino)-; 927801-54-5; Boc-Phe(2-COOH)-OH (related derivative)
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Aminophenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.