Description

4'-[(tert-Butoxycarbonyl)Amino]Biphenyl-3-Carboxylic Acid, also known as 4'-[(tert-Butoxycarbonyl)Amino]-3-Carboxybiphenyl or 3-{4-[(tert-Butoxycarbonyl)Amino]Phenyl}Benzoic Acid, is a high-purity, protected amino acid derivative featuring a biphenyl core. This compound serves as a critical building block in advanced organic synthesis, particularly for constructing complex molecules with specific spatial and electronic properties. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by academic and industrial researchers in material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor modulators, and other small-molecule therapeutics.
• Agrochemical Research: Used in constructing advanced scaffolds for new herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Conjugation: The carboxylic acid and Boc-protected amine functionalities allow for its incorporation into peptide backbones or for use as a linker in bioconjugation chemistry.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-fidelity biphenyl derivatives.

Basic Information

Product Name	4'-[(tert-Butoxycarbonyl)Amino]Biphenyl-3-Carboxylic Acid
CAS No.	927801-51-2
Molecular Formula	C18H19NO4
Molecular Weight	313.35 g/mol
Synonyms	4'-[(tert-Butoxycarbonyl)Amino]-3-Carboxybiphenyl; 3-{4-[(tert-Butoxycarbonyl)Amino]Phenyl}Benzoic Acid; 4'-(Boc-amino)biphenyl-3-carboxylic acid; 3-Carboxy-4'-(N-Boc-amino)biphenyl; Biphenyl-3-carboxylic acid, 4'-[(1,1-dimethylethoxy)carbonyl]amino]-; N-Boc-4'-aminobiphenyl-3-carboxylic acid; 4'-(tert-Butoxycarbonylamino)biphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4'-[(tert-Butoxycarbonyl)Amino]Biphenyl-3-Carboxylic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.