Description

4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid is a high-value fluorinated aromatic building block, distinguished by its trifluoromethoxy and benzoic acid functional groups. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable properties like metabolic stability and enhanced lipophilicity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and target binding.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Research: Employed in academic and industrial R&D for exploring new reactions and creating complex molecular architectures in medicinal and synthetic chemistry.
• Ligand & Catalyst Development: Utilized to synthesize novel ligands for catalysis or metal-organic frameworks (MOFs) due to its rigid, functionalized aromatic core.

Basic Information

Product Name	4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid
CAS No.	926220-09-9
Molecular Formula	C14H9F3O3
Molecular Weight	282.22 g/mol
Synonyms	[2'-(Trifluoromethoxy)[1,1'-biphenyl]-4-carboxylic Acid; 4-[2-(Trifluoromethoxy)phenyl]benzoic acid; 2'-(Trifluoromethoxy)biphenyl-4-carboxylic acid; 4-Carboxy-2'-(trifluoromethoxy)biphenyl; Biphenyl-4-carboxylic acid, 2'-(trifluoromethoxy)-; 926220-09-9
EINECS	Contact for details

Quality Control

Our production of 4-[2-(Trifluoromethoxy)Phenyl]Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.