Description

2-(3-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced material synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or aryl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl coupling steps.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl linkages with high efficiency and functional group tolerance.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Ligand & Catalyst Preparation: Can be utilized in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Product Name	2-(3-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	925916-59-2
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	3-Isopropoxyphenylboronic acid pinacol ester; (3-Isopropoxyphenyl)boronic acid pinacol ester; 3-(Isopropoxy)benzeneboronic acid pinacol ester; 3-Isopropoxybenzeneboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[3-(1-methylethoxy)phenyl]-4,4,5,5-tetramethyl-; PINACOL (3-ISOPROPOXYPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 2-(3-Isopropoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥97% (by HPLC/NMR). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.