Description

5-n-Octylthiophene-2-Boronic Acid Pinacol Ester is a high-purity organoboron building block, specifically a thiophene-based boronic ester derivative. This compound is a critical reagent in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed synthesis of biaryl and heteroaryl compounds, widely used in drug discovery and material science.
• Pharmaceutical Intermediate: Serves as a versatile building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those containing thiophene motifs.
• Organic Electronic Materials: Used in the development of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Agrochemical Synthesis: Employed in the creation of advanced herbicides, fungicides, and insecticides that require specific thiophene-based structures.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D labs for exploring new synthetic pathways and novel organic compounds.

Basic Information

Item	Detail
Product Name	5-n-Octylthiophene-2-Boronic Acid Pinacol Ester
CAS No.	925424-90-4
Molecular Formula	C₁₈H₃₁BO₂S
Molecular Weight	322.31 g/mol
Synonyms	2-(5-Octylthiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Octyl-2-thienylboronic Acid Pinacol Ester; 5-Octylthiophene-2-Boronic Acid Pinacol Ester; 2-(5-n-Octyl-2-thienyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Thiophene-2-boronic acid, 5-octyl-, 1,1-dimethylethyl ester; Pinacol 5-Octylthiophene-2-boronate
EINECS	Contact for details

Quality Control

Every batch of 5-n-Octylthiophene-2-Boronic Acid Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive cross-coupling applications. Our quality assurance protocol includes NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.