Description

1-Difluoromethyl-1 H-Pyrazole-3-Carboxylic Acid is a high-value fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its unique difluoromethylated pyrazole core is essential for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoromethyl group can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of novel fluorinated organic materials and polymers with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Product Name	1-Difluoromethyl-1 H-Pyrazole-3-Carboxylic Acid
CAS No.	925179-02-8
Molecular Formula	C5H4F2N2O2
Molecular Weight	162.10 g/mol
Synonyms	1-(Difluoromethyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 1-(difluoromethyl)-; Difluoromethylpyrazole-3-carboxylic Acid; 1-Difluoromethyl-1H-pyrazole-3-carboxylic acid; 925179-02-8
EINECS	Contact for details

Quality Control

Every batch of 1-Difluoromethyl-1 H-Pyrazole-3-Carboxylic Acid is produced and tested under strict quality management protocols to ensure consistency and purity for research and scale-up applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.