Description

2-(4-Bromo-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and polymer development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and boronic acids/esters, widely used in pharmaceutical synthesis.
• Pharmaceutical Intermediate: Serves as a versatile building block in the research and development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific aryl-boronate functionalities.
• Material Science & OLED Development: Employed in the synthesis of organic light-emitting diode (OLED) materials and other advanced organic electronic compounds.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable tool for academic and industrial R&D chemists exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	2-(4-Bromo-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	924964-16-9
Molecular Formula	C14H20BBrO2
Molecular Weight	311.02 g/mol
Synonyms	4-Bromo-2,5-dimethylbenzeneboronic acid pinacol ester; (4-Bromo-2,5-dimethylphenyl)boronic acid pinacol ester; 2-(4-Bromo-2,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-2,5-dimethylphenylboronic acid pinacol ester; Pinacol (4-Bromo-2,5-dimethylphenyl)boronate; 4-Bromo-2,5-dimethylphenyl-Bpin; 924964-16-9; B-(4-Bromo-2,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.