Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-[Tris(1-Methylethyl)Silyl]- is a high-value, organosilane-protected heterocyclic building block, specifically designed for advanced synthetic chemistry. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides with specific mode-of-action profiles.
• Material Science Precursor: Serves as a starting material for creating organic semiconductors and advanced functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Cross-Coupling Reactions: The aldehyde and chloro groups provide handles for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Academic & Contract Research: Essential reagent for exploratory organic synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	924655-39-0
Molecular Formula	C17H25ClN2OSi
Molecular Weight	336.93 g/mol
Synonyms	4-Chloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 4-Chloro-1-triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde; 1-Triisopropylsilyl-4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; TIPS-4-Chloro-7-azaindole-5-carboxaldehyde; 4-Chloro-1-[(triisopropylsilyl)]-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde; 924655-39-0; 4-Chloro-1-TIPS-7-azaindole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 4-Chloro-1-[Tris(1-Methylethyl)Silyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.