Description

1H-Isoindole, 2,3-Dihydro-5-(Trifluoromethyl)-, Hydrochloride is a high-value trifluoromethylated isoindoline derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling the efficient construction of complex molecules, particularly in the development of novel pharmaceuticals and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-purity building block for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of novel organic electronic materials, dyes, and functional polymers.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the design of chemical probes and enzyme inhibitors for target validation studies.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	1H-Isoindole, 2,3-Dihydro-5-(Trifluoromethyl)-, Hydrochloride
CAS No.	924304-74-5
Molecular Formula	C9H9ClF3N
Molecular Weight	223.62 g/mol
Synonyms	5-(Trifluoromethyl)isoindoline hydrochloride; 2,3-Dihydro-5-(trifluoromethyl)-1H-isoindole hydrochloride; 5-Trifluoromethylisoindoline HCl; 1H-Isoindole, 2,3-dihydro-5-(trifluoromethyl)-, hydrochloride (1:1); 5-(Trifluoromethyl)-2,3-dihydro-1H-isoindole hydrochloride; Isoindoline, 5-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Isoindole, 2,3-Dihydro-5-(Trifluoromethyl)-, Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.