Description

3-Chloro-6-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive carboxylic acid group, a halogen substituent, and a trifluoromethyl group, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to incorporate the benzothiophene scaffold and fluorine atoms into novel active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent for creating novel polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probe Development: Employed to build molecular probes and inhibitors for studying enzyme function and biological pathways in R&D settings.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	3-Chloro-6-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid
CAS No.	923849-73-4
Molecular Formula	C10H4ClF3O2S
Molecular Weight	280.65 g/mol
Synonyms	3-Chloro-6-(trifluoromethyl)benzo[b]thiophene-2-carboxylic acid; 2-Benzothiophenecarboxylic acid, 3-chloro-6-(trifluoromethyl)-; 3-Chloro-6-trifluoromethyl-1-benzothiophene-2-carboxylic acid; 3-Chloro-6-trifluoromethylbenzo[b]thiophene-2-carboxylic acid; 923849-73-4; 3-Chloro-6-(trifluoromethyl)thianaphthene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-6-(Trifluoromethyl)-1-Benzothiophene-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) with complete analytical data are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.