Description

1-(2-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid is a high-value fluorinated pyrrole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which combines a fluorinated aromatic ring with a substituted pyrrole carboxylic acid, enabling precise structural modifications for target molecule synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorophenyl and pyrrole motifs can contribute to biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Item	Details
Product Name	1-(2-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid
CAS No.	923781-31-1
Molecular Formula	C13H12FNO2
Molecular Weight	233.24 g/mol
Synonyms	2,5-Dimethyl-1-(2-fluorophenyl)-1H-pyrrole-3-carboxylic acid; 1H-Pyrrole-3-carboxylic acid, 1-(2-fluorophenyl)-2,5-dimethyl-; 1-(2-Fluorophenyl)-2,5-dimethylpyrrole-3-carboxylic acid; 2-Fluoro-α,α,α',α'-tetramethyl-1H-pyrrole-3-acetic acid (tautomeric form); 923781-31-1; Fluorophenyl dimethylpyrrole carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-2,5-Dimethyl-1H-Pyrrole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.