Description

3,3-Difluorocyclohexanamine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoro-substituted cyclohexane scaffold, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Key intermediate in the synthesis of pharmaceutical candidates, particularly those targeting central nervous system (CNS) disorders.
• Building block for advanced agrochemicals, where the fluorine atoms can enhance metabolic stability and bioavailability.
• Precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Starting material for the development of specialty polymers and advanced materials with tailored properties.
• Research chemical for studying structure-activity relationships (SAR) in medicinal chemistry programs.
• Intermediate in the production of fluorinated liquid crystals or electronic chemicals.

Basic Information

Product Name	3,3-Difluorocyclohexanamine
CAS No.	921753-34-6
Molecular Formula	C6H11F2N
Molecular Weight	135.16 g/mol
Synonyms	3,3-Difluorocyclohexylamine; Cyclohexanamine, 3,3-difluoro-; 3,3-Difluorocyclohexan-1-amine; 3,3-Difluorocyclohexaneamine; 1-Amino-3,3-difluorocyclohexane; 3,3-Difluoro-1-cyclohexanamine
EINECS	Contact for details

Quality Control

Our 3,3-Difluorocyclohexanamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its amine functionality and fluoride content, it should be kept separate from strong acids and oxidizing agents. The container must be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.