Description

2,2-Difluorocyclopentan-1-Amine CAS NO 921753-24-4 is a high-purity, fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclopentane ring with geminal fluorine atoms, makes it a valuable precursor for creating novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the creation of specialty polymers and advanced materials, where the fluorinated cyclopentane unit can impart unique thermal and chemical resistance properties.
• Fluorine Chemistry Research: An essential compound for academic and industrial research exploring new methodologies in fluorination and the development of fluorinated scaffolds.

Basic Information

Product Name	2,2-Difluorocyclopentan-1-Amine
CAS No.	921753-24-4
Molecular Formula	C5H9F2N
Molecular Weight	121.13 g/mol
Synonyms	2,2-Difluorocyclopentanamine; 1-Amino-2,2-difluorocyclopentane; Cyclopentanamine, 2,2-difluoro-; 2,2-Difluorocyclopentylamine; 2,2-Difluoro-1-cyclopentanamine; 2,2-Difluorocyclopentan-1-amine hydrochloride (salt form); 921753-24-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluorocyclopentan-1-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Impurities (HPLC)	Individual ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.