Description

2-Bromo-5-Chloropyridine-4-Carboxaldehyde is a high-value halogenated pyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both bromo and chloro substituents alongside an aldehyde group, enables precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular wires.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and library production.

Basic Information

Product Name	2-Bromo-5-Chloropyridine-4-Carboxaldehyde
CAS No.	921630-14-0
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	5-Chloro-2-bromopyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 2-bromo-5-chloro-; 2-Bromo-5-chloro-4-formylpyridine; 2-Bromo-5-chloroisonicotinaldehyde; 921630-14-0; 2-Bromo-5-chloropyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloropyridine-4-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.