Description

1H-Imidazole, 2-Fluoro-, 3-Oxide is a specialized fluorinated and N-oxidized derivative of the imidazole heterocycle, representing a high-value synthetic intermediate. This compound matters for its unique electronic properties conferred by the fluorine atom and N-oxide moiety, which are critical for modulating the reactivity and biological activity of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by researchers in material science exploring advanced functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes where the fluorinated N-oxide structure can enhance binding or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom improves lipophilicity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, leveraging the electron-withdrawing and coordinating properties of the N-oxide group.
• Material Science Research: Investigated for incorporation into organic electronic materials, such as OLEDs or conductive polymers, due to its modified electronic structure.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, where its distinct structure allows for selective labeling or modulation.

Basic Information

Item	Details
Product Name	1H-Imidazole, 2-Fluoro-, 3-Oxide
CAS No.	921604-83-3
Molecular Formula	C3H3FN2O
Molecular Weight	102.07 g/mol
Synonyms	2-Fluoro-1H-imidazole 3-oxide; 2-Fluoroimidazole 3-oxide; 2-Fluoro-1H-imidazole-3-ol, 1-oxide; 2-Fluoroimidazole N-oxide; 1H-Imidazole-3-oxide, 2-fluoro-; Fluorinated imidazole N-oxide; 2-F-Imidazole-3-O
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 2-Fluoro-, 3-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.