Description

2-(4-Fluorophenyl)Thiazole-5-Carbaldehyde is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the thiazole and fluorophenyl motifs.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or activity-based probes for studying biological processes.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories worldwide.
• Scale-up & Process Chemistry: Suitable for optimization from milligram to kilogram scale for clinical trial material (CTM) production.

Basic Information

Product Name	2-(4-Fluorophenyl)Thiazole-5-Carbaldehyde
CAS No.	921124-57-4
Molecular Formula	C10H6FNO1S
Molecular Weight	207.22 g/mol
Synonyms	5-Formyl-2-(4-fluorophenyl)thiazole; 2-(4-Fluorophenyl)-1,3-thiazole-5-carboxaldehyde; 2-(p-Fluorophenyl)thiazole-5-carbaldehyde; 4-Fluorophenylthiazole-5-carboxaldehyde; (4-Fluorophenyl)thiazole-5-carbaldehyde; Thiazole-5-carbaldehyde, 2-(4-fluorophenyl)-; 921124-57-4
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.