Description

2-(4-Isopropyl-Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for research and development in advanced fields. This compound is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers focused on creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic scaffolds.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, electron transport materials, and light-emitting molecules for advanced electronic devices.
• Chemical Biology & Probe Development: Utilized for creating labeled compounds and molecular probes for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CROs and CDMOs offering bespoke chemical synthesis services to the life sciences industry.

Basic Information

Product Name	2-(4-Isopropyl-Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	919496-58-5
Molecular Formula	C18H30BN3O2
Molecular Weight	331.27 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[4-(propan-2-yl)piperazin-1-yl]pyridine; 2-(4-Isopropylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Isopropyl-1-piperazinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(4-Isopropylpiperazin-1-yl)pyridine-5-boronic acid pinacol ester; 919496-58-5; Boric acid, B-[2-[4-(1-methylethyl)-1-piperazinyl]-5-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 2-(4-Isopropyl-Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.