Description

N,n-Dimethyl-1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanamine is a high-value, functionalized pyridine derivative containing a pinacol boronate ester group, making it a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon and carbon-heteroatom bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester moiety is specifically designed for palladium-catalyzed cross-coupling with aryl or vinyl halides, enabling precise molecular assembly.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and affinity tags for studying biological systems and protein function.
• Ligand Synthesis for Catalysis: Acts as a starting material for constructing sophisticated nitrogen-containing ligands used in homogeneous catalysis.

Basic Information

Product Name	N,n-Dimethyl-1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanamine
CAS No.	919347-18-5
Molecular Formula	C16H27BN2O2
Molecular Weight	290.21 g/mol
Synonyms	3-((Dimethylamino)methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinemethanamine, N,N-dimethyl-; N,N-Dimethyl-1-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]methanamine; 3-(Dimethylaminomethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 919347-18-5; (5-((Dimethylamino)methyl)pyridin-3-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-1-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.