Description

3,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced pyridazine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyridazine core.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine
CAS No.	919197-88-9
Molecular Formula	C10H13BCl2N2O2
Molecular Weight	275.94 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dichloropyridazine; 3,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-diazine; 3,6-Dichloro-4-pyridazineboronic acid pinacol ester; 919197-88-9; 4-(Pinacolatoboryl)-3,6-dichloropyridazine
EINECS	Contact for details

Quality Control

Our 3,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during weighing to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.