Description

1-(4-Bromo-3-Iodo-Phenyl)-Ethanone is a high-purity halogenated aromatic ketone building block, essential for advanced organic synthesis. Its distinct molecular structure, featuring both bromine and iodine substituents, provides unique reactivity for selective cross-coupling reactions and functional group transformations. This compound is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and complex organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions due to its reactive halogen atoms.
• Chemical Derivatization: The ketone functional group allows for further transformations, including reductions, oxidations, and nucleophilic additions.
• Academic & Industrial R&D: Employed in research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	1-(4-Bromo-3-Iodo-Phenyl)-Ethanone
CAS No.	919124-08-6
Molecular Formula	C8H6BrIO
Molecular Weight	324.94 g/mol
Synonyms	4'-Bromo-3'-iodoacetophenone; 1-(4-Bromo-3-iodophenyl)ethan-1-one; 4-Bromo-3-iodoacetophenone; Ethanone, 1-(4-bromo-3-iodophenyl)-; 4'-Bromo-3'-iodoacetophenone; 1-Acetyl-4-bromo-3-iodobenzene; p-Bromo-m-iodoacetophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-3-Iodo-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.