Description

5-Chloro-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, synthetically versatile boronic ester derivative of an indole scaffold. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products.
• Material Science Research: Building block for developing organic electronic materials and functional polymers.
• Chemical Biology Probes: Enables the labeling and study of biological targets and pathways.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.
• Process Chemistry: Employed in route scouting and optimization for scalable manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-Chloro-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	919119-60-1
Molecular Formula	C₁₅H₁₉BClNO₂
Molecular Weight	291.58 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-chloro-2-methyl-1H-indole; 5-Chloro-2-methyl-1H-indole-7-boronic acid pinacol ester; 5-Chloro-2-methylindole-7-boronic acid pinacol ester; 919119-60-1; 5-Chloro-2-methyl-7-(pinacolatoboryl)-1H-indole; 7-Borono-5-chloro-2-methyl-1H-indole pinacol ester; 5-Chloro-2-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and structural identity suitable for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent hydrolysis of the boronic ester. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.