Description

1,3-Bis(2,4,6-Trimethylphenyl)-4,5-Dihydroimidazol-2-Ylidene[2-(I-Propoxy)-5-(N,n-Dimethylaminosulfonyl)Phenyl]Methyleneruthenium(Ii)Dichloride is a highly specialized, second-generation Grubbs-Hoveyda type ruthenium-based olefin metathesis catalyst. This compound is engineered for superior thermal stability and extended catalyst lifetime, enabling more efficient and controlled polymerization and ring-closing metathesis reactions. It is a critical advanced material for R&D and production in pharmaceutical intermediates, specialty polymers, and fine chemical synthesis, where precise reaction control is paramount.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key ring-closing metathesis (RCM) and cross-metathesis (CM) steps in the production of complex active pharmaceutical ingredients (APIs).
• Specialty Polymer Chemistry: Catalyst for ring-opening metathesis polymerization (ROMP) to create advanced materials with specific mechanical and thermal properties.
• Fine Chemical Manufacturing: Facilitating the synthesis of complex organic molecules, including natural products and fragrances, in research and scale-up environments.
• Agrochemical Research: Used in the development of novel compounds with potential biological activity.
• Material Science R&D: Key reagent for developing new functional polymers and smart materials.
• Academic & Industrial Catalysis Research: A benchmark catalyst for studying and developing new metathesis methodologies.

Basic Information

Product Name	1,3-Bis(2,4,6-Trimethylphenyl)-4,5-Dihydroimidazol-2-Ylidene[2-(I-Propoxy)-5-(N,n-Dimethylaminosulfonyl)Phenyl]Methyleneruthenium(Ii)Dichloride
CAS No.	918870-76-5
Molecular Formula	C35H46Cl2N2O3RuS
Molecular Weight	752.78 g/mol
Synonyms	Grubbs-Hoveyda II Catalyst; Hoveyda-Grubbs Catalyst 2nd Generation; (1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium (sulfonated derivative); Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][(2-isopropoxy-5-(N,N-dimethylaminosulfonyl)phenyl)methylene]ruthenium(II); Sulfonated Hoveyda-Grubbs Catalyst; Ru-based metathesis catalyst.
EINECS	Contact for details

Quality Control

Every batch of our ruthenium catalyst is produced and tested under strict quality management protocols to ensure exceptional purity and consistent catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (by NMR/HPLC), residual solvent content, and identity confirmation. Our quality system is designed to meet the exacting standards required for GMP-influenced manufacturing and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture. For long-term stability, storage at -20°C is recommended.

Specification

Item	Specification
Appearance	Dark green to brown crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/NMR)	≥ 95%
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.