Description

4-Chloro-3-Ethylphenylboronic Acid is a versatile organoboron compound widely used as a key synthetic intermediate in cross-coupling reactions. Its value lies in enabling the efficient construction of complex biaryl structures, which are crucial scaffolds in advanced material and pharmaceutical research. This high-purity building block is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

This boronic acid derivative serves as a critical reagent in modern synthetic chemistry, with primary applications including:

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for creating carbon-carbon bonds to synthesize complex biaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligand frameworks for catalytic systems.
• Chemical Biology Probes: Serves as a handle for bioconjugation and the development of molecular probes.

Basic Information

Product Name	4-Chloro-3-Ethylphenylboronic Acid
CAS No.	918810-94-3
Molecular Formula	C8H10BClO2
Molecular Weight	184.43 g/mol
Synonyms	(4-Chloro-3-ethylphenyl)boronic acid; 4-Chloro-3-ethylbenzeneboronic acid; 3-Ethyl-4-chlorophenylboronic acid; Boronic acid, B-(4-chloro-3-ethylphenyl)-; 918810-94-3; 4-Chloro-3-ethylphenyl-B(OH)2; (3-Ethyl-4-chlorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Ethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.