Description

4-(4-Iodophenyl)Butan-2-One is a versatile aryl ketone building block characterized by its iodinated phenyl ring. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for compounds targeting central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4-(4-Iodophenyl)Butan-2-One
CAS No.	918540-55-3
Molecular Formula	C10H11IO
Molecular Weight	274.10 g/mol
Synonyms	1-(4-Iodophenyl)butan-2-one; 4'-Iodobutyrophenone; 4-Iodophenyl Ethyl Ketone; 4-Iodobutyrophenone; p-Iodobutyrophenone; Butan-2-one, 4-(4-iodophenyl)-; 4-(4-Iodophenyl)-2-butanone
EINECS	Contact for details

Quality Control

Our 4-(4-Iodophenyl)Butan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.