Description

3-Bromo-4-Fluorophenylacetylene is a high-purity halogenated phenylacetylene building block, essential for advanced organic synthesis. This compound matters because it enables the precise construction of complex molecular architectures through versatile cross-coupling and cycloaddition reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Key pharmaceutical intermediate for the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Critical building block in agrochemical research for developing new herbicides, fungicides, and pesticides with enhanced efficacy.
• Precursor for functional materials, including organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Versatile substrate for Sonogashira coupling reactions to create conjugated systems and extended aromatic structures.
• Used in click chemistry applications, such as copper-catalyzed azide-alkyne cycloaddition (CuAAC), for bioconjugation and polymer synthesis.
• Starting material for synthesizing fluorinated and brominated specialty chemicals with unique electronic and physical properties.

Basic Information

Product Name	3-Bromo-4-Fluorophenylacetylene
CAS No.	918487-39-5
Molecular Formula	C8H4BrF
Molecular Weight	199.02 g/mol
Synonyms	1-Bromo-2-fluoro-4-ethynylbenzene; 4-Ethynyl-2-fluoro-1-bromobenzene; 2-Fluoro-4-ethynyl-1-bromobenzene; 3-Bromo-4-fluoroethynylbenzene; (3-Bromo-4-fluorophenyl)ethyne; 4-Bromo-3-fluorophenylacetylene (isomer check); 918487-39-5; BFP acetylene derivative
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorophenylacetylene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.