Description

5-Fluoro-6-Methylnicotinaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both aldehyde and fluorine functionalities, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Synthesis: Employed for constructing sophisticated ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Utilized as a probe or labeling reagent due to its reactive aldehyde group, which can form stable conjugates.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, fluorinated compounds on scale.

Basic Information

Product Name	5-Fluoro-6-Methylnicotinaldehyde
CAS No.	917835-70-2
Molecular Formula	C8H6FNO
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-6-methyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 5-fluoro-6-methyl-; 5-Fluoro-6-methylnicotinaldehyde; 5-Fluoro-6-methylpyridine-3-carbaldehyde; 6-Methyl-5-fluoronicotinaldehyde; 5-Fluoro-6-methyl-3-formylpyridine; 5-Fluoro-6-methyl-3-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-6-Methylnicotinaldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.