Description

n-(2,2,2-Trifluoroethyl)Cyclohexanamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a cyclohexyl backbone with a trifluoroethylamine moiety, which can impart desirable properties like metabolic stability and altered lipophilicity to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the amine functionality for metal coordination or activation.
• Material Science Research: Employed in the synthesis of fluorinated polymers, resins, or liquid crystals, where the amine group can facilitate polymerization or functionalization.
• Chemical Biology Probe: Useful for incorporating a fluorinated tag into bioactive molecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	n-(2,2,2-Trifluoroethyl)Cyclohexanamine
CAS No.	917771-47-2
Molecular Formula	C8H14F3N
Molecular Weight	181.20 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)cyclohexanamine; Cyclohexanamine, N-(2,2,2-trifluoroethyl)-; 2,2,2-Trifluoro-N-cyclohexylethanamine; 1-Cyclohexyl-2,2,2-trifluoroethylamine; N-Cyclohexyl-2,2,2-trifluoroethanamine; 2,2,2-Trifluoroethylcyclohexylamine; (Cyclohexylamino)(trifluoro)ethane
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethyl)Cyclohexanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR, MS), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.