Description

7-Fluorochroman-4-Ol is a fluorinated chroman derivative, a versatile chiral building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in the structural motif that combines a chroman scaffold with a fluorine atom and a hydroxyl group, enabling precise modifications for developing novel bioactive molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, asymmetric synthesis, and the development of new fluorinated active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Asymmetric Catalysis: Serves as a valuable ligand precursor or chiral auxiliary in stereoselective synthesis to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore the impact of fluorination on the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Fluorine Chemistry: An important substrate for studying fluorination reactions and the synthesis of complex fluoroorganic molecules.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring the chroman structure.

Basic Information

Product Name	7-Fluorochroman-4-Ol
CAS No.	917248-49-8
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	7-Fluorochroman-4-ol; 4-Chroman-4-ol, 7-fluoro-; 7-Fluoro-3,4-dihydro-2H-1-benzopyran-4-ol; 7-Fluoro-4-hydroxy-3,4-dihydro-2H-chromene; 7-Fluoro-4-hydroxychroman; 7-Fluoro-4-hydroxy-3,4-dihydro-2H-1-benzopyran
EINECS	Contact for details

Quality Control

Our 7-Fluorochroman-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical data. Our quality commitment ensures batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.