Description

4-(3-Ethylureido)-3-Methoxyphenylboronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the palladium-catalyzed formation of carbon-carbon bonds, enabling the construction of complex molecular architectures.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and other advanced functional materials where precise molecular structure is paramount.
• Chemical Biology & Probe Synthesis: Facilitates the creation of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(3-Ethylureido)-3-Methoxyphenylboronic Acid, Pinacol Ester
CAS No.	917111-46-7
Molecular Formula	C16H25BN2O4
Molecular Weight	320.20 g/mol
Synonyms	4-(3-Ethylureido)-3-methoxyphenylboronic acid pinacol ester; 3-Methoxy-4-(3-ethylureido)benzeneboronic acid pinacol ester; 4-(N'-Ethylureido)-3-methoxyphenylboronic acid pinacol ester; 4-(3-Ethylureido)-3-methoxybenzeneboronic acid pinacol ester; Pinacol [4-(3-ethylureido)-3-methoxyphenyl]boronate; [4-(3-Ethylureido)-3-methoxyphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-(3-Ethylureido)-3-Methoxyphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates under cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.