Description

Ethyl 1-(Fluoromethyl)Cyclopropanecarboxylate is a high-value fluorinated cyclopropane derivative, a crucial building block in modern synthetic chemistry. This compound matters for its unique structural motif, which combines the ring strain of a cyclopropane with the electronic and steric properties of a fluoromethyl group, enabling the synthesis of complex molecules with tailored properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorinated cyclopropane ring can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with specific surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new C-F bond formation reactions and the properties of fluorinated small molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring fluorinated building blocks.

Basic Information

Product Name	Ethyl 1-(Fluoromethyl)Cyclopropanecarboxylate
CAS No.	917095-87-5
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	1-(Fluoromethyl)cyclopropanecarboxylic acid ethyl ester; Ethyl 1-(fluoromethyl)cyclopropanecarboxylate; Ethyl (1-(fluoromethyl)cyclopropyl)carboxylate; Cyclopropanecarboxylic acid, 1-(fluoromethyl)-, ethyl ester; 1-Fluoromethyl-cyclopropanecarboxylic acid ethyl ester; 917095-87-5
EINECS	Contact for details

Quality Control

Our Ethyl 1-(Fluoromethyl)Cyclopropanecarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by GC, HPLC, and NMR. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are properly sealed when not in use and stored away from heat and ignition sources. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.