Description

4-Bromo-2-Fluoro-5-Methylbenzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the bromo and fluoro substituents enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a core building block for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Dye & Pigment Production: Employed in the synthesis of specialized dyes and pigments where halogenation alters light absorption and stability.
• Organic Ligand Preparation: Useful for creating chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Methylbenzaldehyde
CAS No.	916792-23-9
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2-Fluoro-5-methyl-4-bromobenzaldehyde; 4-Bromo-2-fluoro-5-methyl-benzaldehyde; 5-Methyl-4-bromo-2-fluorobenzaldehyde; Benzaldehyde, 4-bromo-2-fluoro-5-methyl-; 916792-23-9; AI3-32455; AKOS040759957; CTK8G7118
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Methylbenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to support your R&D and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.