Description

1,3,2-Dioxaborolane, 2-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its value lies in providing a protected, air-stable boronic acid equivalent that facilitates complex cross-coupling reactions essential for constructing sophisticated molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create complex, functionalized aromatic compounds that are precursors to new herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for constructing charge-transport or emissive layers in advanced display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate or tridentate ligands for transition metal catalysis.
• Polymer Chemistry: A monomer or cross-linking agent in the production of specialty polymers with tailored electronic or mechanical properties.
• Academic & Contract Research: Essential reagent for methodological development and exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	916747-53-0
Molecular Formula	C₁₆H₂₄BBrO₂
Molecular Weight	339.08 g/mol
Synonyms	2-(2-Bromo-5-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Bromo-5-tert-butylphenyl)boronic acid pinacol ester; 2-Bromo-5-tert-butylbenzeneboronic acid pinacol ester; 2-Bromo-5-(tert-butyl)phenylboronic acid pinacol ester; Pinacol (2-bromo-5-tert-butylphenyl)boronate; tert-Butylphenylboronic acid pinacol ester, 2-bromo-; Boronic acid, B-[2-bromo-5-(1,1-dimethylethyl)phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Every batch of our 1,3,2-Dioxaborolane, 2-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]-4,4,5,5-Tetramethyl- undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles, with standard specifications typically meeting or exceeding 97% purity (by HPLC). Our quality management system supports traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.