Description

Boronic Acid, B-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]- is a high-purity, synthetically valuable organoboron compound characterized by its sterically hindered aryl bromide and tert-butyl substituents. This specific molecular architecture makes it a crucial advanced intermediate for constructing complex molecules via cross-coupling reactions, particularly Suzuki-Miyaura couplings. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in constructing biaryl motifs common in many therapeutic agents.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile electrophilic or nucleophilic partner (depending on the synthetic strategy) for forming carbon-carbon bonds with high selectivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that require specific, sterically defined structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis or as a precursor for functional materials.
• Organic Electronic Materials: A potential monomer or intermediate in the synthesis of conjugated polymers and small molecules for OLEDs or organic semiconductors.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	Boronic Acid, B-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]-
CAS No.	916747-52-9
Molecular Formula	C12H16BBrO2
Molecular Weight	283.97 g/mol
Synonyms	(2-Bromo-5-tert-butylphenyl)boronic acid; 2-Bromo-5-tert-butylbenzeneboronic acid; B-(2-Bromo-5-tert-butylphenyl)boronic acid; 2-Bromo-5-(1,1-dimethylethyl)benzeneboronic acid; 2-Bromo-5-tert-butylphenylboronic acid; Boronic acid, B-[2-bromo-5-(1,1-dimethylethyl)phenyl]-; [2-Bromo-5-(tert-butyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, B-[2-Bromo-5-(1,1-Dimethylethyl)Phenyl]- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot is analyzed via HPLC, NMR (1H, 13C, 11B), and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.