Description

(2-(Hydroxymethyl)Thiophen-3-Yl)Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide candidates through palladium-catalyzed cross-coupling methodologies.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as conductive polymers and organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	(2-(Hydroxymethyl)Thiophen-3-Yl)Boronic Acid
CAS No.	916673-46-6
Molecular Formula	C5H7BO3S
Molecular Weight	157.98 g/mol
Synonyms	3-Thiopheneboronic acid, 2-(hydroxymethyl)-; (2-(Hydroxymethyl)-3-thienyl)boronic acid; 2-(Hydroxymethyl)thiophene-3-boronic acid; 3-Borono-2-(hydroxymethyl)thiophene; 916673-46-6; (2-Hydroxymethyl-thiophen-3-yl)-boronic acid
EINECS	Contact for details

Quality Control

Our (2-(Hydroxymethyl)Thiophen-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.