Description

1-(4-(Trifluoromethyl)Cyclohexyl)Ethanone is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a cyclohexyl backbone and a trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF₃ group can improve biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and stability.
• Advanced Polymer Modifiers: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for constructing complex, fluorinated molecular architectures in academic and industrial R&D.

Basic Information

Product Name	1-(4-(Trifluoromethyl)Cyclohexyl)Ethanone
CAS No.	916481-56-6
Molecular Formula	C₉H₁₃F₃O
Molecular Weight	194.19 g/mol
Synonyms	4'-(Trifluoromethyl)cyclohexyl methyl ketone; 1-[4-(Trifluoromethyl)cyclohexyl]ethanone; 4-(Trifluoromethyl)cyclohexanemethyl ketone; p-(Trifluoromethyl)cyclohexyl methyl ketone; 4-Trifluoromethylcyclohexyl methyl ketone; 1-Acetyl-4-(trifluoromethyl)cyclohexane
EINECS	Contact for details

Quality Control

Our production of 1-(4-(Trifluoromethyl)Cyclohexyl)Ethanone adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical syntheses. All materials are characterized by modern analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.