Description

4-Methoxy-2-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-functional benzyl bromide derivative, distinguished by its methoxy and trifluoromethyl substituents which confer unique electronic and steric properties. This compound serves as a critical alkylating agent and versatile chemical building block for the synthesis of complex organic molecules. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the 4-methoxy-2-(trifluoromethyl)benzyl moiety.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Used to create specialized ligands for catalysis and molecular recognition studies in both academic and industrial research.
• Material Science Precursor: Intermediate in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Life Science Research: Employed as a biochemical probe or labeling reagent in medicinal chemistry and drug discovery programs.

Basic Information

Item	Detail
Product Name	4-Methoxy-2-(Trifluoromethyl)Benzyl Bromide
CAS No.	916420-86-5
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	1-(Bromomethyl)-4-methoxy-2-(trifluoromethyl)benzene; α-Bromo-4-methoxy-α,α,α-trifluoro-o-xylene; 2-(Trifluoromethyl)-4-methoxybenzyl bromide; (4-Methoxy-2-(trifluoromethyl)phenyl)methyl bromide; 4-Methoxy-α,α,α-trifluoro-o-tolyl bromide; 4-Methoxy-2-trifluoromethylbenzyl bromide; 2-Trifluoromethyl-4-methoxybenzyl bromide
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and all materials are fully characterized. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.