Description

3-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Propionic Acid is a high-purity fluorinated aromatic propionic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart enhanced metabolic stability, lipophilicity, and binding affinity in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine-tuning the properties of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in areas targeting inflammation, central nervous system (CNS) disorders, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), enhancing thermal stability and electronic properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent in coupling reactions and as a scaffold for constructing complex, fluorinated molecular architectures in academic and industrial R&D.
• Material Science Research: Employed in the development of specialty polymers and coatings where fluorination is required for specific chemical resistance or surface properties.

Basic Information

Product Name	3-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Propionic Acid
CAS No.	916420-37-6
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	2-Fluoro-α-methyl-3-(trifluoromethyl)benzenepropanoic Acid; 3-(2-Fluoro-3-(trifluoromethyl)phenyl)propanoic Acid; 2-Fluoro-3-trifluoromethylhydrocinnamic Acid; β-(2-Fluoro-3-trifluoromethylphenyl)propionic Acid; 916420-37-6; 3-(2-Fluoro-3-(trifluoromethyl)phenyl)propionic Acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this fluorinated intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and every batch is analyzed to meet exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with each shipment to ensure reliable performance in your downstream synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, appropriate chemical-resistant materials should be used for handling and storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.