Description

1-Bromo-3,3,4,4,4-Pentafluorobut-1-Ene CAS NO 916134-86-6 is a highly fluorinated bromoalkene building block, valued for its unique reactivity profile and the introduction of a pentafluoroethyl group. This compound is essential for advanced synthetic chemistry, particularly in the development of novel fluorinated materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing fluorinated drug candidates, leveraging the fluorine effect to modulate bioavailability, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced fluorinated pesticides and herbicides, where the pentafluoroethyl group can enhance biological activity and environmental persistence.
• Fluoropolymer Modification: Serves as a functional monomer or cross-linking agent in the development of specialty fluoropolymers with tailored surface properties and chemical resistance.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated liquid crystals and organic semiconductors for display technologies and electronic devices.
• Cross-Coupling Reactions: Acts as an effective coupling partner in palladium-catalyzed reactions (e.g., Heck, Suzuki) for introducing fluorinated vinyl segments into organic frameworks.
• Radical Chemistry & Polymerization: Utilized as an initiator or chain-transfer agent in controlled radical polymerization processes to create fluorinated polymers.

Basic Information

Product Name	1-Bromo-3,3,4,4,4-Pentafluorobut-1-Ene
CAS No.	916134-86-6
Molecular Formula	C4H2BrF5
Molecular Weight	224.96 g/mol
Synonyms	3,3,4,4,4-Pentafluoro-1-bromobut-1-ene; 1-Bromo-3,3,4,4,4-pentafluoro-1-butene; 1-Butene, 1-bromo-3,3,4,4,4-pentafluoro-; (3,3,4,4,4-Pentafluorobut-1-en-1-yl)bromide; Pentafluoroethyl vinyl bromide; Vinyl bromide, pentafluoroethyl-; CF3CF2CH=CHBr
EINECS	Contact for details

Quality Control

Our 1-Bromo-3,3,4,4,4-Pentafluorobut-1-Ene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.8 g/mL
Boiling Point	~85-90°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.