Description

2-(Benzofuran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key intermediate in the development of active pharmaceutical ingredients (APIs), crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly those containing benzofuran scaffolds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl couplings.
• Material Science: Serves as a monomer or precursor in the creation of organic semiconductors, OLED materials, and conductive polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new C-C bond formation methodologies and complex molecule synthesis.
• Ligand and Catalyst Development: Can be utilized to create novel bidentate ligands or incorporated into metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced intermediates for various high-value industries.

Basic Information

Product Name	2-(Benzofuran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	915412-92-9
Molecular Formula	C₁₆H₂₁BO₃
Molecular Weight	272.15 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuran; Benzofuran-4-boronic acid pinacol ester; 2-(Benzofuran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Boronobenzofuran pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran; 915412-92-9; Pinacol 4-benzofuranboronate
EINECS	Contact for details

Quality Control

Our 2-(Benzofuran-4-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.