Description

5-Cyano-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[B]Thiophene is a high-value, multi-functional heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct complex heterocyclic cores found in modern pesticides and herbicides.
• Organic Light-Emitting Diodes (OLEDs): Building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Monomer for creating specialty polymers with tailored electronic or optical properties.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands used in homogeneous catalysis.
• Academic & Contract Research: Enables exploratory research in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	5-Cyano-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[B]Thiophene
CAS No.	915402-11-8
Molecular Formula	C15H16BNO2S
Molecular Weight	285.17 g/mol
Synonyms	2-(5-Cyanobenzo[b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzo[b]thiophene-2-boronic acid, 5-cyano-, pinacol ester; 5-Cyanobenzo[b]thiophene-2-boronic acid pinacol ester; 5-Cyano-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzothiophene; 915402-11-8; 5-CN-BT-2-Bpin
EINECS	Contact for details

Quality Control

Our production of 5-Cyano-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[B]Thiophene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and LC-MS to confirm identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.