Description

3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane is a high-value, multi-functional organoboron and organosilicon building block designed for advanced synthetic chemistry. This compound matters because it combines the versatility of a pinacol boronate ester with the stability and reactivity of a protected alkyne, enabling precise carbon-carbon bond formation in complex molecule assembly. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for cross-coupling reactions and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and conjugated systems in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-alkyne architectures.
• Material Science & OLED Development: Serves as a monomer or building block for creating conjugated polymers, organic semiconductors, and light-emitting materials for electronic devices.
• Ligand & Catalyst Design: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Chemical Biology & Probe Synthesis: Utilized for labeling biomolecules or creating molecular probes due to its orthogonal reactivity and potential for further functionalization.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane
CAS No.	915402-03-8
Molecular Formula	C19H29BO2Si
Molecular Weight	328.33 g/mol
Synonyms	Trimethyl((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)silane; 3-((Trimethylsilyl)ethynyl)phenylboronic acid pinacol ester; 3-Ethynylphenylboronic acid pinacol ester, trimethylsilyl-protected; 3-((Trimethylsilyl)ethynyl)benzeneboronic acid pinacol ester; TMS-EthynylphenylBPin; 915402-03-8; (3-((Trimethylsilyl)ethynyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports compliance with ISO, GMP, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.