Description

Boronic Acid, B-[3,5-Bis(Trimethylsilyl)Phenyl]- is a highly functionalized organoboron compound featuring sterically hindered trimethylsilyl (TMS) protecting groups. This advanced synthetic intermediate is critical for enabling complex cross-coupling reactions, particularly in environments demanding enhanced stability and selectivity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing sophisticated molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing the sterically protected 3,5-bis(trimethylsilyl)phenyl moiety into complex molecules, useful in pharmaceutical and materials science research.
• Pharmaceutical Intermediate: Employed in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates where the TMS groups provide temporary protection or influence pharmacokinetic properties.
• Advanced Materials Synthesis: Used in the development of organic electronic materials, such as OLEDs and OFETs, where the precise control of molecular structure is essential for performance.
• Agrochemical Research: Serves as a precursor for novel crop protection agents and herbicides, leveraging its unique boron-substituted aromatic system.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	Boronic Acid, B-[3,5-Bis(Trimethylsilyl)Phenyl]-
CAS No.	915230-75-0
Molecular Formula	C15H29BO2Si2
Molecular Weight	308.38 g/mol
Synonyms	[3,5-Bis(trimethylsilyl)phenyl]boronic acid; B-[3,5-Bis(trimethylsilyl)phenyl]boronic acid; (3,5-Bis(trimethylsilyl)phenyl)boronic acid; 3,5-Bis(trimethylsilyl)benzeneboronic acid; 915230-75-0; Boronic acid, B-[3,5-bis(trimethylsilyl)phenyl]-; (3,5-Di(trimethylsilyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[3,5-Bis(Trimethylsilyl)Phenyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.