Description

Ethyl 2-(4,4-Difluorocyclohexyl)Acetate is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the difluorocyclohexyl moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in display technologies and organic light-emitting diodes.
• Advanced Polymer Modification: Employed to introduce fluorinated cyclohexyl groups into polymer chains, modifying properties like chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis & Medicinal Chemistry Research: A versatile reagent for constructing complex, fluorinated heterocycles and exploring structure-activity relationships (SAR) in academic and industrial labs.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of novel, high-value aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	Ethyl 2-(4,4-Difluorocyclohexyl)Acetate
CAS No.	915213-54-6
Molecular Formula	C10H16F2O2
Molecular Weight	206.23 g/mol
Synonyms	Ethyl (4,4-Difluorocyclohexyl)acetate; Acetic acid, 2-(4,4-difluorocyclohexyl)-, ethyl ester; 2-(4,4-Difluorocyclohexyl)acetic Acid Ethyl Ester; Ethyl 4,4-Difluorocyclohexylacetate; Ethyl (4,4-Difluorocyclohexyl)ethanoate; 915213-54-6; Ethyl 2-(4,4-Difluorocyclohexyl)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4,4-Difluorocyclohexyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.