Description

3-Chloropyridine-4-Boronic Acid, Neopentyl Glycol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key synthetic intermediate, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions under mild conditions. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for constructing complex heterocyclic scaffolds and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific chloropyridine motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring protected boronate functionality.

Basic Information

Product Name	3-Chloropyridine-4-Boronic Acid, Neopentyl Glycol Ester
CAS No.	915070-52-9
Molecular Formula	C11H15BClNO2
Molecular Weight	239.51 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-chloropyridine; 3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Chloro-4-pyridineboronic acid neopentyl glycol ester; 3-Chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol ester of 3-chloro-4-pyridinylboronic acid; 3-Chloro-4-boronopyridine neopentyl glycol ester; 3-Chloro-4-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Chloropyridine-4-Boronic Acid, Neopentyl Glycol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.